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人工血管管壁涂层生物材料的生物相容性评价
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【中医学论文集】作者：王康，史宏灿，陆世春，孙超，贺建胜，裴昶【摘要】 对人工血管管壁涂层的生物材料进行生物相容性的实验评价。按照国际标准，对相关单个和混合材料进行急性全身毒性试验、热源试验、溶血试验和细胞毒性试验。 结果表明：本实验涉及的生物材料胶原蛋白、聚乳酸以及混合组分材料均符合生物相容性评价实验的安全标准。说明胶原蛋白和聚乳酸作为复合型人工血管管壁涂层材料具有生物相容性和安全性，可为临床产品的研制提供依据。
【关键词】 人工血管涂层材料；生物材料；生物相容性；胶原蛋白；聚乳酸
Abstract：To make evaluation far biocompatibility of the materials which is covered on the vascular prosthesis surface.With the international standardizations, some experiments for the materials were done, include acute systemic toxicity test , pyrogen test ，hemolysis test and cytotoxicity test.Results showed that the collagen protein,L-polylactic acid and the mixed materials were all consistent with the safety control.It proves that the collagen protein and L-polylactic acid are with biocompatibiliy and safety for coating on the surface of vascular prosthesis.
Key words：Converage of vascular prosthesis; Biomateria
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