| | | 一种复配型玛咖保健品对小鼠免疫功能的影响
| | 临床医学检验论文 作者:金文闻,张永忠,敖明章,余龙江 【摘要】 目的临床医学检验论文 探讨一种添加了西洋参总皂苷的临床医学检验论文玛咖保健品对小鼠细胞免疫功能、体液免疫功能、巨噬细胞吞噬功能以及NK细胞活性的影响。方法 实验组小鼠每日分别灌胃高、中、低剂量的复配玛咖根干粉,连续30天,然后分别进行ConA诱导的小鼠淋巴细胞转化实验、小鼠半数溶血值(HC50)测定、小鼠腹腔巨噬细胞吞噬鸡红细胞实验和NK细胞活性测定。结果 与对照组比较,各剂量组均能提高ConA诱导的小鼠淋巴细胞转化能力、小鼠巨噬细胞吞噬能力和小鼠NK细胞活性(P<0.05 或 P<0.01),在中、高剂量组能提高小鼠的半数溶血值(P<0.01)。结论 复配玛咖根干粉对小鼠各项免疫功能指标均有显著提高作用,可见该复配型玛咖保健品具有增强免疫力的功效。 【关键词】 玛咖;免疫功能;保健品 【Abstract】 Objective To evaluate the effects of a Maca healthy product compounded with ginsenosides on cell-mediated immune function,humoral immune function,macrophage phago-function and NKC activity of mice.Methods Mice in the treatment group were perfused by the test compound in three different dose (high: 1.000 g/kg BW;medium:0.200 g/kg BW;low:0.020 g/kg BW) continuously for 30 days,then the research on the experiments on immune regulation,including ConA-induced lymphocyte transformation test total hemolytic complement assay (HC50 assay),peritoneal macrophage phago-function mensuration and NKC activity assay were taken.Results In comparison with control group,the lymphocyte transformation rate,the ability of phagocytosis and the NKC activity significantly increased in the treatment group in all dose (P<0.05 or P<0.01), and the HC50 value significantly increased in high and medium dose (P<0.01).Conclusion Powdered Maca root compounded with ginsenosides could significantly improve the immune function of mice,and the compounded Maca healthy product possessed the effects in enhancing the immunity. 【Key words】 Maca (Lepidium meyenii.);immune function;healthy product 玛咖(Maca, Lepidium meyenii.Walp)为十字花科独行菜属的一年生或两年生草本植物,原产于秘鲁海拔3500米以上的安第斯山区。数千年来玛咖根作为食物、草药被广泛用于增强精力,抗疲劳,提高生育力,治疗女性更年期综合征,抗抑郁和抗贫血等[1~3],近十年更在国际上被开发成多种保健食品,受到全球保健人士的青睐[4]。我国也在3年前引入了玛咖保健品,但目前产品功能单一,与国际上产品在功效上有比较大差距。国际上已经流行将玛咖根粉进行浓缩或者进行复配,这不仅提高了玛咖保健品的功效,更赋予“Maca”这一国际知名品牌产品更多的适用范围,例如将玛咖与鹿茸、银杏提取物等天然产品复配后得到的产品,均得到国际消费者的喜爱。
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