|
骨纤维结构不良病变组织雌激素受体和增殖细胞核抗原检测及临床意义
|
|
【西药学见习论文】 作者:牛彦辉,王臻,郑修存,吴作栋,沈强,张立明【关键词】 ,,纤维发育不良Detection and significance of estrogen receptor and proliferating cell nuclear antigen in tissues of fibrous dysplasia of bone 【Abstract】 AIM: To investigate the relation between the clinical biological behavior and the expression of estrogen receptor (ER) and proliferating cell nuclear antigen (PCNA) in the tissues of fibrous dysplasia of bone (FDB). METHODS: Ninetyeight cases wrer surgically treated, pathologically confirmed as having fibrous dysplasia and followed up. The primary operation specimens were randomly selected and divided into recurrence group (n=24) and cured group (n=24), children group (n=26) and adult group(n=22). The ER and PCNA in the specimens were detected with monoclonal antibody to ER or PCNA by immunohistochemistry. RESULTS: The general positive expression rate o
|
|
|