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母乳喂养与婴儿HCV感染关系的META分析
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【关键词】 肝炎,丙型；META分析；疾病传播,垂直
A META analysis of association between breastfeeding and risk for infant hepatitis C virus infection
【Abstract】 AIM: To investigate the association between breastfeeding and infant hepatitis C virus (HCV) infection. METHODS: China biological medicine database (CBMD) Founder Database, and Medline citations were surveyed to obtain literatures eligible for METAanalysis. Criteria for enrollment of published literatures for META analysis was based on the principles by Abdolmaleky HMs standard［1］. Odd ratios(OR) were calculated and summarized by fixed effect model or random effect model. The heterogeneity of OR was assessed using a χ2 test. The association was evaluated using the OR values. All data were calculated automatically with REVMAN 4.2 software. RESULTS: By searching in Medline and CBMD, 120 articles were enrolled for further identification. Thirtyseven reviews on this field were excluded. Abstracts of remaining articles were carefully read, and finally 6 articles met the enrollment standards. Results from META analysis suggested that there was not a significant association of breastfeeding with infant HCV infection with OR being 0.60 (95%CI: 0.22-1.60). CONCLUSION: Breastfeeding did not increase the risk for infant to acquire the infection of HCV.
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