| | | 山东大汶河流域居民恶性肿瘤死因调查
| | 药学科研论文
作者：王涛，郭晓雷，张吉玉，付振涛，鹿子龙，李维卡，徐爱强，孙建东，李卫
【关键词】 大汶河；山东省；恶性肿瘤,死因；流行病学调查
摘要： 目的药学科研论文 了解山东省大汶河主干流域居民恶性肿瘤的药学科研论文死亡水平及其分布。方法 采用横断面研究方法，对2002～2004年大汶河主干流域及其对照区居民进行以恶性肿瘤为主的全死因回顾性调查，以国际疾病分类标准(ICD-10)进行死因编码和根本死因的推断，计算死亡率、死亡构成等指标。结果 共调查了8个县(市、区)54个乡镇，其中研究区41个乡镇，对照区13个乡镇。研究区年均人口为2227271人，恶性肿瘤年均标化死亡率为14064／10万；对照区年均人口为498121人，恶性肿瘤年均标化死亡率为139.42／10万。恶性肿瘤死亡居全死因顺位第1位，且均以食管癌为其首位肿瘤死因。大汶河流域上游地区标化死亡率(12143／10万)极显著低于中下游地区(16108／10万)(χ2=501218，P<0001)。结论 大汶河流域恶性肿瘤特别是食管癌死亡率较高，尤以中下游为最高，应进一步开展相关研究以便采取针对性控制措施。
关键词： 大汶河；山东省；恶性肿瘤，死因；流行病学调查
Investigation on death cause of malignant tumors among residents in areas of Dawen river in Shandong province
Abstract： Objective To describe the mortality of malignant tumors and its distribution among residents in the main trunk-stream areas of Dawen river in Shandong province.Methods With the cross-sectional study method,a retrospective investigation for all death causes mainly comprised of malignant tumor was carried out among residents in the main trunk-stream areas of Dawen river and its contro1 areas from 2002 to 2004.The death causes were coded based on ICD-10，and the ultimate death causes were concluded.The statistic indexes were calculated with mortality rate and its component，etc.Results 54 townships including 41 as study areas and 13 as control areas were investigated in 8 counties of the main trunk-stream areas of Dawen river.The yearly average population and standardized mortality rate of malignant tumors were 2227271 persons and 140.64 per 100000 population among residents in study areas，and 498121 persons and 139.42 per 100000 population among residents in control areas.The mortality of malignant tumors with the first rank of esophageal cancer was firstly ranked among all death causes in both areas.The yearly standardized mortality rate among residents in the upriver areas(121.43 per 100000 population) was significantly lower than that in me mid-river and downriver areas(161.08 per 100000 population)(χ2=5012.18，P<0.001).Conclusion The mortality rate of malignant tumors especially esophageal cancer among residents in the main trunk-stneam areas of Dawen river was higher，especially in the mid-river and downriver areas.Further researches should be carried out to take appropriate measures for the malignant tumors control.
Key words： Dawen river;Shandong province；malignant tumors;death cause；epidemiological investigation
大汶河发源于山东省莱芜、沂源、新泰山区，自东向西流经5个市的12个县(市、区)，其主干流域位于莱芜市和泰安市境内。历史上，流域内的肥城市、宁阳县等为肿瘤高发区〔1〕。随着近年来工业化、城市化进程的加快，沿岸工矿企业和居民生活污水的排放造成了大汶河沿岸浅层地下水污染，致使中下游大部分河段水质为劣V类(主要适用于农业用水及一般景观用水)，已基本不适宜饮用，而以食管癌为主的恶性肿瘤死亡一直居高不下。为了解大汶河主干流域恶性肿瘤死亡水平及其分布状况，为今后在该地区开展肿瘤防治研究提供依据，我们于2005年9～12月对大汶河主干流域居民进行以恶性肿瘤为主的全死因回顾性调查。结果报告如下。
|
| | |
| | | | <<<<<全文未完>>>>> 全文字数约3871字 | |
| | |
| |
|
教育论文中心