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脑梗死与循环免疫复合物的相关性研究
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【摘要】 目的 探讨循环免疫复合物与脑梗死的关系。方法 采用酶联免疫吸附试验（ELISA）方法测定脑梗死患者血中巨细胞病毒抗体（CMV-IgG与CMV-IgM）及衣原体抗体（CP-IgG），并与健康对照组比较。结果 脑梗死组循环免疫复合物显著升高（P﹤0.01），其中CMV-IgM在发病早期明显升高(P﹤0.01)，随着病情康复，其水平逐渐下降。CMV-IgG和CP-IgG也呈现类似变化。结论 脑梗死患者血中CMV-IgG、CMV-IgM和CD-IgG升高，循环复合物对脑梗死的发生有一定的不良影响。
【关键词】 脑梗死；巨细胞病毒抗体IgG、IgM；衣原体抗体IgG；循环免疫复合物
The study of the relationship between the cerebral infaction and the circulating immune complexes
【Abstract】 Objective To explore the relationship between the circulating immune complexes (CIC) and the cerebral infarction.Methods Serum anti-cytomegalovirus antibodies ( CMV-IgG and CMV-IgM ) and anti-Chlamydia pneumonia antibody ( CP-IgG ) in 140 cases were determinated by ELISA. The results were compared with the control group.Results The circulating immune complexes (CIC ) in the cerebral infarction group was increased. The anti-cytomegalovirus antibodies were increased significantly in the early stage. There was significantly difference between cerebral infarction group and the control group ( P﹤0.01 ). But the CIC at late stage were reduced in the cerebral infarction group( P﹤0.01 ). And the CMV-IgM and CP-IgG were so.Conclusion The CMV-IgG and IgM and CP-IgG were increased in cerebral infarction patients.The increased total CIC may accelerate the disease.
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