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男性肝硬化患者血清性激素水平的分析
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[摘要] 目的:了解男性肝硬化患者血清性激素水平的变化情况及临床意义。 方法:检测67例肝硬化患者和34例正常健康人员的血清卵泡刺激素(FSH)、黄体生成素(LH)、雌二醇(E2)、睾酮(T)及催乳素(PRL),并进行统计学分析。结果:肝硬化患者血清T、E2水平较正常对照组显著性降低(P<0.01),血清PRL水平较正常对照组显著性增高(P<0.01)。 结论:男性肝硬化患者体内存在性激素水平的失衡和紊乱,检测血清中T、E2和PRL水平对肝硬化的诊断有一定价值。 [关键词] 肝硬化;性激素;分析 Analysis of Serum Levels of Sex Hormones in the Male Patients with Hepatic Cirrhosis Abstract: Objective To investigate the changes and clinical significance of serum levels of sex hormones in male patients with hepatic cirrhosis. Methods The follicle stimulating hormone(FSH), luteinizing hormone(LH), estradiol(E2), testosterone(T) and prolactin(PRL) of 67 male patients with hepatic cirrhosis and 34 men in the control group were examined for statistical analysis. Results The serum levels of T, E2 and PRL in male patients with hepatic cirrhosis were significantly different to the control group (P<0.01). Conclusion There are disorders and imbalances of sex hormones in male patients with hepatic cirrhosis, and the detection of T, E2 and PRL may have some value to hepatic cirrhosis diagnosis.
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