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含锶磷酸钙骨水门汀的理化性能和水化产物
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【药学毕业论文】【关键词】 磷酸钙;,碳酸;,锶中图分类号:,,,,,,,,R318.08,,,,摘要: 目的 探讨用碳酸锶对α磷酸钙骨水门汀系统进行改性后的理化性能和水化产物 分析 。 方法 在α磷酸钙骨水门汀粉末中加入碳酸锶改性,考察其凝固时间、压缩强度、溶解率及pH值的变化,采用X射线衍射、红外光谱、扫描电镜分析其水化产物及表面形貌。结果 添加适量的碳酸锶不会妨碍α磷酸三钙(αTCP)的水化进程,凝固时间适于临床操作,压缩强度和溶解率增大,水化反应后呈弱碱性,水化产物为含锶的缺钙型碳酸基HA。结论 适量的碳酸锶可改善α磷酸钙骨水门汀系统的理化性能,水化产物与天然骨组织的矿物相成分接近,可能有利于植入材料与骨的结合。 关键词: 磷酸钙; 碳酸; 锶 ABSTRACT: Objective The physicochemical properties and hydrating product of αtricalcium phosphate cement modified by strontium carbonate was investigated. Methods In this study αtricalcium phosphate(αTCP) cement was modified by strontium carbonate, the settingtime, compressive strength, rate of dissolution and value of pH were investigated.The hydrating product was analyzed by Xray diffraction infrared spectum and electron microscope. Results Strontium carbonate had no interference with αTCP cement’s hydrating process. The settingtime could meet t
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