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仙人掌药用成分的提取及其镇痛作用的实验研究
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【药学实习报告范文】作者:韦国锋, 李振中, 黄祖良, 何有成【关键词】 仙人掌;,,药用成分;,,提取;,,药理;,,镇痛摘要:目的对仙人掌药用成分的提取工艺及镇痛作用进行探讨。 方法 采用乙醇提取,醋酸乙酯等有机溶剂萃取,经硅胶柱层分离,得到淡黄色物质,并对该物质进行了化学定性 分析 和小鼠镇痛作用实验。结果经化学定性分析,表明这种药用成分中含有黄酮类物质,其镇痛作用与阿司匹林和生理盐水比较:扭体法χ2分别为5.19,9.68(P<0.05或0.001);温浴法P<0.01或P<0.001。结论仙人掌植物中含有黄酮类物质,对小鼠具有显著的镇痛作用。 关键词:仙人掌; 药用成分; 提取; 药理; 镇痛 Studies on Extraction and Analgesic Effect of Medicinal Components in Opuntia dillenii Haw Abstract:ObjectiveTo investigate the extract processing and the analgesic effect of medicinal components in Opuntia dillenii Haw.Methods The chemical quantitative analysis and the analgesic effect on mice were carried out on a primrose yellow material which was extracted by ethanol, ethyl acetate and chromatographically separated by silica gel column.ResultsA flavonoid chemical compound was found and the χ2 were 5.19( P< 0.05 or 0.01) in writhing tests(P< 0.01 or
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