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Liposomal Doxorubicin, Cyclophosphamide, and Etoposide and Antiretroviral Therapy for Patients with AIDS-Related Lymphoma: A Pilot Study
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【西医学论文下载】作者：Sara Combsa, Nancy Neilb, David M. Aboulafiaa,c【关键词】 Non-Hodgkin’s,lymphoma
a University of Washington School of Medicine, Seattle, Washington, USA; b Ovation Research Group, Highland Park, Illinois, USA, and University of Washington School of Public Health, Seattle, Washington, USA; c Virginia Mason Medical Center, Seattle, Washington, USA
Key Words. Non-Hodgkin’s lymphoma ; HIV/AIDS ; Antiretroviral therapy ; Chemotherapy
ABSTRACT
Purpose. To evaluate in a pilot study the safety and efficacy of liposomal doxorubicin, cyclophosphamide, and etoposide (LACE) when combined with antiretroviral therapy (ART) in patients with AIDS-related lymphoma (ARL). The impact of HIV viral control on therapy and survival was also assessed.
Patients and Methods. Between 1994 and 2005, 40 patients at Virginia Mason Medical Center were diagnosed with ARL. Twelve r
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