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涂丝型双嘧达莫选择电极的研制与应用
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【药学论文网】【摘要】 报道了一种以双嘧达莫与碘分子形成的缔合物为电活性物的PVC膜双嘧达莫涂丝选择电极,测定了双嘧达莫片的含量。电极的线性响应范围为1.0×10-2 ~4.0×10-5mol/L,级差电位为56mV/pC,检测限为2.6×10-5mol/L。该电极响应迅速,重现性好,结果与药典法相符。 【关键词】 离子选择电极 双嘧达莫 涂丝 测定 Preparation and Application of Coated Wire Polyvinyl Chloride Membranedipyridamole Selective Electrode Abstract In this paper, a new coated wire polyvinyl chloride membranedipyridamole selective electrode based on dipyridamole and iodine molecular association complex is reported. The electrode showed Nernst response for dipyridamole ranges between 1.0×10-2~4.0×10-5mol/L with a slope of 56 mV/pC. The detection limit is 2.6×10-5mol/L. The electrode has fast respons and good reproducibility. The electrode has been used for the determination of dipyridamole in medicinal tablet by the standard curve method. The procedures of this method are simple and the reseuts obtained agree with those of ph
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