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山楂和山楂叶对大鼠血清中SOD和GSH-Px的影响
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【专科药学毕业论文】作者:张淑华,褚金花,王晖,黄佩力,宣登峰,吴萍,于秋红【摘要】 目的 为 研究 山楂和山楂叶的抗氧化作用。 方法 本实验选用Wistar雄性大鼠作为研究对象。使用高脂饲料喂养的同时,用不同剂量的山楂和山楂叶提取物灌胃。5周后测定大鼠血清中的超氧化物歧化酶(SOD)以及血清中谷胱甘肽过氧化物酶(GSH-Px)活性;同时对山楂和山楂叶的抗氧化指标进行比较。结果 山楂和山楂叶提取物能增强GSH-Px 的活性,提高SOD的活力;山楂叶GSH-Px的活力高于山楂。结论 本文提示山楂和山楂叶具有抗氧化的作用。 【关键词】 山楂和山楂叶;SOD;GSH-Px Effects of haw and hawthorn leaf extracts on serum SOD and GSH-Px in rats 【Abstract】 Objective Male Wistar rats were used as experimental subject to investigate the antioxidation effect of haw and hawthorn leaf extracts.Methods The rats were feeding on a high-fat diet for 5 weeks, while different doses of the two kinds of extracts were administered respectively by gavage once a day. Then serum SOD and GSH-Px activity were determined.Results It showed that both haw and hawthorn leaf extracts can increase the activity of SOD and GSH-Px,the activity of hawthorn leaf was higher than that of
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